Peptide Profiles

What Is AOD-9604? A Research Profile

AOD-9604 is one of the more distinctive peptides in metabolic research, mostly because of where it comes from. It is not a random sequence, it is a fragment of a much larger, well-known molecule. This profile explains what AOD-9604 is, how it relates to human growth hormone, and why it draws research interest, kept clear and accurate.

What AOD-9604 is

AOD-9604 is a synthetic peptide fragment. The name AOD stands for anti-obesity drug, a label from its early research history, and it is also known as HGH fragment 176-191. That second name is the more informative one. It tells you exactly what the peptide is: a specific slice of the human growth hormone molecule, corresponding to amino acids 176 through 191 of that much larger protein. In other words, AOD-9604 is a small piece copied from the tail end of HGH, made on its own.

The connection to human growth hormone

Human growth hormone is a large protein of 191 amino acids. Researchers noticed that a specific short region near the end of that protein was associated with the parts of HGH studied in lipid and fat metabolism, while the rest of the molecule carries its other activities. AOD-9604 isolates just that region. The idea behind building the fragment was to study that particular segment on its own, separated from the full hormone. That is the whole reason it exists as a distinct compound: it is the interesting fragment, cut out and made by itself.

Why it is studied in lipid research

Because AOD-9604 comes from the region of HGH linked to fat metabolism, it is studied in that context: how the fragment interacts with the pathways involved in the handling and breakdown of lipids. It is grouped with metabolic research compounds for exactly this reason. As with any research peptide, the value here is that a small, defined fragment can be produced consistently and studied cleanly, without the complexity of the entire parent protein.

How it fits among metabolic research compounds

Compound What it is Research theme
AOD-9604 Fragment of HGH (176-191) Lipid metabolism
MOTS-c Mitochondrial-derived peptide Mitochondrial and metabolic pathways
5-Amino-1MQ Small molecule NNMT enzyme inhibition

They differ in structure and origin, but all three sit within the same broad area of how cells manage energy and fat, which is why they are often discussed together.

Why the fragment name matters

The label HGH fragment 176-191 is worth understanding because it is more precise than the marketing name. Those numbers pin down exactly which stretch of the parent hormone the peptide represents, which means two suppliers describing the same fragment should be describing the same sequence. When you compare AOD-9604 products, that shared definition is your reference point: identity confirmation by mass spectrometry should tie back to the mass expected for the 176-191 fragment, not to the full hormone or some other slice. A clear name is the first small check before the paperwork.

What to look for when sourcing AOD-9604

AOD-9604 is a defined peptide fragment, so the same quality checklist applies as for any research peptide:

  • Identity: mass spectrometry confirming the fragment matches its intended sequence and mass.
  • Purity: an HPLC percentage with a chromatogram showing a clean main peak.
  • Per-lot COA: documentation tied to the actual batch you receive, not a stock sample.
  • Storage: kept cold, dry, and away from light to stay stable.

Buying research peptides in Canada from LYFE Science

LYFE Science is a Canadian supplier. Every compound is checked for identity and purity by HPLC and mass spectrometry, with a certificate of analysis available per lot, so the paperwork matches the vial you actually receive. We ship nationwide by Canada Post, flat $25 and free over $150, in neutral packaging, with same-day dispatch on orders paid before noon Eastern and one to three business days to most of Canada. Payment is by Interac e-Transfer or crypto (BTC, ETH, SOL, USDC, USDT).

Curious about the wider metabolic research category? Start with our peptide guide for the fundamentals, then browse the full catalogue on the shop page.

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